Description
Evidence Tier · Randomized Controlled Trials
A maintenance dose of vitamin D3 in an oil-based softgel.
What It Does
Supports normal immune function, calcium absorption, and muscle function.*
How It Works
Vitamin D3 is converted in the liver to 25(OH)D, the circulating form, and in tissues to its active hormone, which regulates calcium absorption and immune cell function.
Why This Form
Cholecalciferol in oil for absorption. 2,000 IU is a daily maintenance dose for most adults without a need for testing first.
Clinical Evidence
A dose-response study quantified the rise in serum 25(OH)D from daily cholecalciferol.¹ A meta-analysis of 25 randomized trials examined daily or weekly vitamin D and acute respiratory infections.²
What The Evidence Does Not Show
The benefit in the meta-analysis was concentrated in people with low baseline vitamin D. People with adequate levels may see little change.
Supplement Facts
| Per Serving | Amount | % DV |
|---|---|---|
| Vitamin D3 (as cholecalciferol) | 50 mcg (2,000 IU) | 250% |
† Daily Value not established.
Other Ingredients
Softgel (gelatin, glycerin, water), soybean oil, corn oil.
Warnings
Consult your physician if pregnant, nursing, or taking medication. Keep out of reach of children. Do not use if the safety seal is damaged or missing. Store in a cool, dry place.
References
- Heaney RP, Davies KM, Chen TC, Holick MF, Barger-Lux MJ. Human serum 25-hydroxycholecalciferol response to extended oral dosing with cholecalciferol. Am J Clin Nutr. 2003;77(1):204-210. Creighton University and Boston University. PubMed 12499343
- Martineau AR, Jolliffe DA, Hooper RL, et al. Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data. BMJ. 2017;356:i6583. Queen Mary University of London. PubMed 28202713
Institution names identify where the cited research was conducted. University Vitamins is not affiliated with or endorsed by these institutions. Our Research Standard →
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
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