Description
Evidence Tier · Emerging Evidence
Nicotinamide mononucleotide, a direct precursor of NAD+, at 500 mg per capsule.
What It Does
Supports cellular NAD+ levels and healthy aging.*
How It Works
NAD+ is a coenzyme in energy metabolism and a substrate for sirtuins and DNA repair enzymes. NAD+ levels decline with age. NMN is converted to NAD+ in one enzymatic step.
Why This Form
500 mg sits inside the 250 to 900 mg range tested in human trials.
Clinical Evidence
A randomized, placebo-controlled trial at Washington University gave 250 mg NMN daily for 10 weeks to postmenopausal women with prediabetes and measured muscle insulin sensitivity.¹ A dose-ranging trial tested 300, 600 and 900 mg daily for 60 days in healthy middle-aged adults.²
What The Evidence Does Not Show
Human trials are short and small. Blood NAD+ rises reliably, but effects on aging outcomes in people are not established.
Supplement Facts
| Per Serving | Amount | % DV |
|---|---|---|
| β-Nicotinamide mononucleotide | 500 mg | † |
† Daily Value not established.
Other Ingredients
HPMC (vegetable capsule), microcrystalline cellulose, silicon dioxide, magnesium stearate.
Warnings
Consult your physician if pregnant, nursing, or taking medication. Keep out of reach of children. Do not use if the safety seal is damaged or missing. Store in a cool, dry place.
References
- Yoshino M, Yoshino J, Kayser BD, et al. Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women. Science. 2021;372(6547):1224-1229. Washington University School of Medicine in St. Louis. PubMed 33888596
- Yi L, Maier AB, Tao R, et al. The efficacy and safety of β-nicotinamide mononucleotide (NMN) supplementation in healthy middle-aged adults: a randomized, multicenter, double-blind, placebo-controlled, parallel-group, dose-dependent clinical trial. GeroScience. 2023;45(1):29-43. National University of Singapore and Vrije Universiteit Amsterdam (industry-sponsored trial). PubMed 36482258
Institution names identify where the cited research was conducted. University Vitamins is not affiliated with or endorsed by these institutions. Our Research Standard →
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
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