Description
Contributes to normal energy-yielding metabolism, normal nervous system function, normal cardiac function, and normal psychological function.
How It Works
Thiamine pyrophosphate is the cofactor for pyruvate dehydrogenase, alpha-ketoglutarate dehydrogenase and transketolase — three control points in the oxidation of glucose.
Why This Form
Water-soluble thiamine relies on an active intestinal transporter that saturates, which caps how much additional intake can reach tissue. Benfotiamine is lipid-soluble and bypasses that ceiling, reaching higher tissue thiamine levels in comparative human studies. We include both.
What we rejected: High-dose thiamine HCl alone. Past the transporter ceiling, additional intake produces little additional tissue thiamine.
The Research Behind It
Comparative human bioavailability studies between thiamine salts and benfotiamine, with erythrocyte transketolase activity as the measured endpoint.
What The Evidence Does Not Show
The endpoint here is an enzyme activity marker. Cognitive and energy outcomes in already-replete adults are not established, and we do not claim them.
Supplement Facts
| Per Serving | Amount | % DV |
|---|---|---|
| Thiamine (as thiamine hydrochloride) | 50 mg | 4,167% |
| Benfotiamine (lipid-soluble thiamine derivative) | 150 mg | † |
† Daily Value not established. Percent Daily Values are based on a 2,000 calorie diet.
Other Ingredients
Microcrystalline cellulose (bulking agent), plant-derived capsule shell.
Every ingredient in this product is listed above. We use no proprietary blends, no titanium dioxide, no artificial colours and no artificial sweeteners. Our Sourcing Standard →
References
A numbered reference list for this formulation is in preparation. In the meantime, you can review the published human trial literature directly:
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
University Vitamins is an independent company. We are not affiliated with, endorsed by, or sponsored by any university or academic institution. Institution names appear solely to identify the source of the research referenced.
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