Description
Contributes to normal energy-yielding metabolism, normal nervous system function, and the reduction of tiredness and fatigue.
How It Works
B vitamins act as coenzymes in the metabolic pathways that release energy from food and support normal nervous system function. Folate and B12 together support normal homocysteine metabolism.
Why This Form
Every B vitamin is supplied in its active coenzyme form: methylcobalamin, L-5-methyltetrahydrofolate, pyridoxal-5-phosphate and riboflavin-5-phosphate. These do not depend on conversion steps that vary between individuals.
What we rejected: Cyanocobalamin and synthetic folic acid, the inexpensive forms used in most B-complex products, and megadoses far beyond the levels studied in humans.
The Research Behind It
High-dose B-complex formulations have been studied in randomized, placebo-controlled trials in healthy adults measuring mood, perceived stress and mental fatigue. Folate and B12 status trials in humans inform the folate and B12 levels chosen.
What The Evidence Does Not Show
B vitamins are water-soluble and generally replete in people eating a varied diet. This is nutritional insurance, not an energy product. The mood findings are modest and come from a small number of trials.
Supplement Facts
| Per Serving | Amount | % DV |
|---|---|---|
| Thiamine (as thiamine HCl) | 25 mg | 2,083% |
| Riboflavin (as riboflavin-5-phosphate) | 25 mg | 1,923% |
| Niacin (as niacinamide) | 50 mg | 313% |
| Vitamin B6 (as pyridoxal-5-phosphate) | 25 mg | 1,471% |
| Folate (as L-5-MTHF) | 680 mcg DFE (400 mcg) | 170% |
| Vitamin B12 (as methylcobalamin) | 500 mcg | 20,833% |
| Biotin | 300 mcg | 1,000% |
| Pantothenic acid (as calcium pantothenate) | 50 mg | 1,000% |
† Daily Value not established.
Other Ingredients
Plant-derived capsule shell, microcrystalline cellulose.
Every ingredient in this product is listed above. We use no proprietary blends, no titanium dioxide, no artificial colours and no artificial sweeteners. Our Sourcing Standard →
Warnings
May cause harmless bright yellow urine due to riboflavin. Consult your physician before use if you are pregnant, nursing or taking medication.
References
You can review the underlying human trial literature directly:
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
University Vitamins is an independent company. We are not affiliated with, endorsed by, or sponsored by any university or academic institution. Institution names appear solely to identify the source of the research referenced.


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